This time, Crash will face the mutated inhabitants of his island, who have been transformed into bloodthirsty beasts by Neo and Nina Cortex, Crash's archenemies. However, Crash is not afraid of them. On the contrary, he will use the special abilities of defeated enemies in the fight against their even more dangerous colleagues. Crash of the Titans will offer a total of 15 unique enemies, against which the player will use not only a set of useful weapons, but also special abilities, including a fire attack or an earthquake. The number of usable special abilities will also increase during the game as the player takes them from defeated enemies. In addition to weapons, Crash will use his hands and feet in combat, and he will be able to combine individual blows into devastating combo attacks. However, there will also be classic hopping, jumping, climbing trees, swinging on a rope and other arcade elements. The game will support cooperative multiplayer, in which a second player will be able to join the game at any time in the role of Carbon Crash, and then together with Crash destroy enemies with double speed using special attacks.